Recent Fundraising Activity
'Many thanks to Angela and the team at life Newpark Pharmacy, Kilkenny for raising money for CROSS.
Ronan Lougnane and his classmates from Cistercian College Roscrea fundraising for CROSS
'May 2017: Ronan Loughnane from Cistercian College, Roscrea, Co. Tipperary and his transition year classmates decided to fundraise for CROSS after he and his father took part in the CROSS rugby legends cycle. They raised money through different fund raising initiatives including car washes. We are extremely grateful to Ronan, his class mates and the teachers in the school for raising such an impressive amount of money for CROSS research. Dr Joanne Lysaght collected the cheque on behalf of CROSS and gave a talk about the cancer research work that is undertaken at Trinity College and St. James's Hospital with the vital funds raised by people such as Ronan.'
Many thanks to Angela and the team at life Newpark Pharmacy, Kilkenny for raising money for CROSS.
Online donations can be made via PayPal. Please click the donate button below. Thanks for your donation.
Friends Of CROSS Charity
Meet Our Friends
Every year our Friends of CROSS help organise the Cross Atlantic Cycle.
The Cross Atlantic Cycle has 3 objectives, each of which has equal importance for CROSS Charity.
1. Cancer Awareness.
Cancer awareness is a key component of Cross Charity’s mission. We use the tour and other initiatives to provide a platform to educate the whole community on the benefits of exercise, diet and weight management in the fight to prevent cancer. During the tour we visit schools, rugby clubs and local community centres.
2. Community Support.
Through our annual cycle we have built a community that works together to support the work of Cross Charity as it battles cancer and its causes. The volunteers, business groups, cyclists and community visits bring together a community of people who work together to achieve a common goal. Our group includes cancer survivors, their friends and relatives, cancer combatants (medical and scientific professionals and their volunteer supporters) who come together in a collaborative way, supporting each other emotionally and professionally throughout the year to make a difference in the battle against and the recovery from cancer.
3. Fund Raising.
Working together we can identify the equipment and resources needed by Cross Charity in their research into cancer causes and cures. Our annual cycle event allows us to generate event profits that are utilised to fund some or all of the requirements specified by the Cross team.
Please visit http://www.crossrugbylegends.com/ for more information.
Tom Conachy
Finance Director
Shane O Dwyer
Chair Friends Of CROSS
Aidan Murphy
Director, Friends Of CROSS
Paul Wallace
Patron Of CROSS Charity
What CROSS Funds
Money raised from the Friends of CROSS charity cycle has contributed to the purchase of some key equipment in the TCD Dept. of Surgery, St. James’s Hospital. This equipment is essential for the ongoing research of the department. Details of the equipment can be found by click on any of the images below.
The QuantStudio 5 Real-Time PCR System is a benchtop instrument that is designed to amplify, detect and quantify DNA. DNA changes are a key feature of cancer and understanding how, why and when these changes occur are crucial elements in our understanding of cancer and other diseases. The QuantStudio 5 allows researchers to analyse DNA changes in human samples, mouse tissue and cells. By gaining an understanding of the genetic changes that occur in disease development, researchers can develop new targeted therapies to treat diseases and improve the lives of patients. The QuantStudio5 machine, house in TTMI, is used solely for the purpose of research and is available to researchers from across TTMI, TCD and St. James’s Hospital.
GelCount is an instrument that allows for accurate imaging, counting and characterising of cell colonies. Cell colonies are formed by proliferating cancer cells grown in vitro. Colonies can be adherent, or non-adherent, suspended either in liquid medium or in 3-D semi-solid matrices. The GelCount machine allows researchers to study the effectiveness of specific treatments on cell survival. This machine and accompanying software is particularly useful when examining the effect of a drug or radiation on proliferating cancer cells. GelCount allows the user to go from colony samples to colony counts and additional statistics such as colony size information. Colonies are imaged, images transferred to a computer, processed and characterised for data analysis. GelCount permits greater experimental throughput and reduces human error and bias associated with manual counting. GelCount is used solely for the purpose of research and is available for use to all TTMI, TCD and St. James’s Hospital staff.
The H35 Hypoxystation is an instrument that allows researchers control the amount of gas, temperature and humidity in a closed workstation environment. It permits the creation of hypoxic (low oxygen levels) and anoxic (no oxygen) conditions within a controlled and sustained workstation. Hypoxia is a feature of many diseases, most notably cancer. Hypoxia of the tumour is a well-established element of cancer. Accurately replicating the tumour microenvironment ex vivo is a major challenge for researchers. The design of the H35 Hypoxystation allows researchers overcome this challenge by granting researchers the ability to accurately control oxygen, carbon dioxide, temperature and humidity. In TTMI, the H35 Hypoxystation is used for research purposes only and it is available to TTMI, TCD, St. James’s researchers across a diverse range of research areas including cancer, inflammation, infection and autoimmune diseases.
Seahorse XFe24 Analyzer
GelCount is an instrument that allows for accurate imaging, counting and characterising of cell colonies. Cell colonies are formed by proliferating cancer cells grown in vitro. Colonies can be adherent, or non-adherent, suspended either in liquid medium or in 3-D semi-solid matrices. The GelCount machine allows researchers to study the effectiveness of specific treatments on cell survival. This machine and accompanying software is particularly useful when examining the effect of a drug or radiation on proliferating cancer cells. GelCount allows the user to go from colony samples to colony counts and additional statistics such as colony size information. Colonies are imaged, images transferred to a computer, processed and characterised for data analysis. GelCount permits greater experimental throughput and reduces human error and bias associated with manual counting. GelCount is used solely for the purpose of research and is available for use to all TTMI, TCD and St. James’s Hospital staff.
The H35 Hypoxystation is an instrument that allows researchers control the amount of gas, temperature and humidity in a closed workstation environment. It permits the creation of hypoxic (low oxygen levels) and anoxic (no oxygen) conditions within a controlled and sustained workstation. Hypoxia is a feature of many diseases, most notably cancer. Hypoxia of the tumour is a well-established element of cancer. Accurately replicating the tumour microenvironment ex vivo is a major challenge for researchers. The design of the H35 Hypoxystation allows researchers overcome this challenge by granting researchers the ability to accurately control oxygen, carbon dioxide, temperature and humidity. In TTMI, the H35 Hypoxystation is used for research purposes only and it is available to TTMI, TCD, St. James’s researchers across a diverse range of research areas including cancer, inflammation, infection and autoimmune diseases.
The Seahorse XFe24 Analyzer measures metabolism of live cells in real-time. The Seahorse machine has the capability of measuring 2 rates of metabolism, oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). These rates are key indicators of mitochondrial respiration and glycolysis and provide a systems-level view of cellular metabolic function in cultured cells and ex vivo human samples. Altered metabolism is a hallmark of many diseases and understanding the role of metabolism in diseases is hugely important. In the Trinity Translational Medicine Institute (TTMI), the Seahorse machine is used exclusively for research purposes and allows researchers to measure the metabolic activity of cells and tissue from a wide range of diseases such as cancer, inflammatory disease and infectious diseases. This allows researchers to gain a better understanding of cell metabolism and whether targeting metabolism may be a novel option for new treatments.
QuantStudio 5 Real-Time PCR System
The H35 Hypoxystation is an instrument that allows researchers control the amount of gas, temperature and humidity in a closed workstation environment. It permits the creation of hypoxic (low oxygen levels) and anoxic (no oxygen) conditions within a controlled and sustained workstation. Hypoxia is a feature of many diseases, most notably cancer. Hypoxia of the tumour is a well-established element of cancer. Accurately replicating the tumour microenvironment ex vivo is a major challenge for researchers. The design of the H35 Hypoxystation allows researchers overcome this challenge by granting researchers the ability to accurately control oxygen, carbon dioxide, temperature and humidity. In TTMI, the H35 Hypoxystation is used for research purposes only and it is available to TTMI, TCD, St. James’s researchers across a diverse range of research areas including cancer, inflammation, infection and autoimmune diseases.
The Seahorse XFe24 Analyzer measures metabolism of live cells in real-time. The Seahorse machine has the capability of measuring 2 rates of metabolism, oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). These rates are key indicators of mitochondrial respiration and glycolysis and provide a systems-level view of cellular metabolic function in cultured cells and ex vivo human samples. Altered metabolism is a hallmark of many diseases and understanding the role of metabolism in diseases is hugely important. In the Trinity Translational Medicine Institute (TTMI), the Seahorse machine is used exclusively for research purposes and allows researchers to measure the metabolic activity of cells and tissue from a wide range of diseases such as cancer, inflammatory disease and infectious diseases. This allows researchers to gain a better understanding of cell metabolism and whether targeting metabolism may be a novel option for new treatments.
The QuantStudio 5 Real-Time PCR System is a benchtop instrument that is designed to amplify, detect and quantify DNA. DNA changes are a key feature of cancer and understanding how, why and when these changes occur are crucial elements in our understanding of cancer and other diseases. The QuantStudio 5 allows researchers to analyse DNA changes in human samples, mouse tissue and cells. By gaining an understanding of the genetic changes that occur in disease development, researchers can develop new targeted therapies to treat diseases and improve the lives of patients. The QuantStudio5 machine, house in TTMI, is used solely for the purpose of research and is available to researchers from across TTMI, TCD and St. James’s Hospital.
GelCount
The Seahorse XFe24 Analyzer measures metabolism of live cells in real-time. The Seahorse machine has the capability of measuring 2 rates of metabolism, oxygen consumption rate (OCR) and extracellular acidification rate (ECAR). These rates are key indicators of mitochondrial respiration and glycolysis and provide a systems-level view of cellular metabolic function in cultured cells and ex vivo human samples. Altered metabolism is a hallmark of many diseases and understanding the role of metabolism in diseases is hugely important. In the Trinity Translational Medicine Institute (TTMI), the Seahorse machine is used exclusively for research purposes and allows researchers to measure the metabolic activity of cells and tissue from a wide range of diseases such as cancer, inflammatory disease and infectious diseases. This allows researchers to gain a better understanding of cell metabolism and whether targeting metabolism may be a novel option for new treatments.
The QuantStudio 5 Real-Time PCR System is a benchtop instrument that is designed to amplify, detect and quantify DNA. DNA changes are a key feature of cancer and understanding how, why and when these changes occur are crucial elements in our understanding of cancer and other diseases. The QuantStudio 5 allows researchers to analyse DNA changes in human samples, mouse tissue and cells. By gaining an understanding of the genetic changes that occur in disease development, researchers can develop new targeted therapies to treat diseases and improve the lives of patients. The QuantStudio5 machine, house in TTMI, is used solely for the purpose of research and is available to researchers from across TTMI, TCD and St. James’s Hospital.
GelCount is an instrument that allows for accurate imaging, counting and characterising of cell colonies. Cell colonies are formed by proliferating cancer cells grown in vitro. Colonies can be adherent, or non-adherent, suspended either in liquid medium or in 3-D semi-solid matrices. The GelCount machine allows researchers to study the effectiveness of specific treatments on cell survival. This machine and accompanying software is particularly useful when examining the effect of a drug or radiation on proliferating cancer cells. GelCount allows the user to go from colony samples to colony counts and additional statistics such as colony size information. Colonies are imaged, images transferred to a computer, processed and characterised for data analysis. GelCount permits greater experimental throughput and reduces human error and bias associated with manual counting. GelCount is used solely for the purpose of research and is available for use to all TTMI, TCD and St. James’s Hospital staff.
H35 Hypoxystation
If you are interested in using some of our equipment please contact Prof. Jacintha O’Sullivan by email: osullij4@tcd.ie
CROSS Medal Winners
Robert Farrell
Joint Winner 2016-2017
Jamie McDonald
Joint Winner 2016-2017
Aisling Heeran
2015-2016